Microsystems to investigate the dynamics of reactive networks Team
Systems biology is a scientific approach under active development. Among other goals, it aims at understanding the emergence of complex phenomena from considering the dynamics of reaction networks in which various biomolecules participate. The study of these structures is often performed relying on relaxation techniques: analyzing the response of systems to a modification of a control parameter enables to hypothesize microscopic mechanisms, to extract thermodynamic and kinetic constants. Our work is part of this general context and our ambition is to setup innovative methodological tools. For most of the projects we devise a dedicated instrumentation based on microfluidics. The latter technology indeed allows one to finely tune the applied stimuli, both in space and time. Finally, our investigations on reaction dynamics span several scales, from the molecule to the organism.